Developmental Basis of Vascular Smooth Muscle Diversity
نویسندگان
چکیده
منابع مشابه
Developmental basis of vascular smooth muscle diversity.
The origins of vascular smooth muscle are far more diverse than previously thought. Lineage mapping studies show that the segmental organization of early vertebrate embryos leaves footprints on the adult vascular system in the form of a mosaic pattern of different smooth muscle types. Moreover, evolutionarily conserved tissue forming pathways produce vascular smooth muscle from a variety of una...
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3 List of publications 4 List of abbreviations 5 1. General aims 9 2. Background 10 2.1. Blood vessels 10 2.1.1. Blood vessel morphology 10 2.1.1.
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Although the primary role of vascular smooth muscle cells (SMCs) is contraction, they exhibit extensive phenotypic diversity and plasticity during normal development, during repair of vascular injury, and in disease states. Results of recent studies indicate that there are unique as well as common transcriptional regulatory mechanisms that control expression of various SMC marker genes in disti...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2007
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.107.141069